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1.
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 329-339
in English | IMEMR | ID: emr-40802

ABSTRACT

Several new pyrazole, pyrazolo [5, 1-c]-1, 2, 4-triazine, pyrimidine and thiazole derivatives were synthesised by the reactions of 2-bromo-1-benzofurylglyoxal-2-[3-phenyl-pyrazol-5-yl]-hydrazone with a variety of reagents. Structures were established by elemental and spectral data


Subject(s)
Triazines/chemistry , Pyrimidines/chemistry , /chemistry
2.
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 351-62
in English | IMEMR | ID: emr-40803

ABSTRACT

The nitrile imine generated by the action of triethylamine on 2-bromo-1-benzofurylglyoxal-2-[3 phenylpyrazol 5-yl]-hydrazone reacted with some Schiff bases, -nitrostyrenes and thiocarboxamidocinnamonitrile derivatives via dipolar cycloaddition reactions to yield several new polyfunctional pyrazole and 1,2,4-triazole derivatives. Structures were confirmed by elemental analysis and spectral data studies


Subject(s)
Pyrazoles/analogs & derivatives , Triazoles/chemical synthesis , Nitriles/chemistry , Imines/chemistry
3.
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 375-385
in English | IMEMR | ID: emr-40805

ABSTRACT

Several new pyrrolidino- and pyrrolo-[4, 3-b] furochromone derivatives were synthesized via the dipolar cycloaddition reactions of some styrylfurochromones with N-arylmaleimide and subsequent dehydrogenation. Structures are confirmed by elemental analysis and spectral data studies


Subject(s)
Pyrrolidines/chemical synthesis , Pyrroles/chemical synthesis , Pyrrolidines/analogs & derivatives , Pyrroles/analogs & derivatives
4.
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 341-349
in English | IMEMR | ID: emr-40830

ABSTRACT

A variety of new pyrazole, pyrrolinopyrazole and pyrazolopyridazine derivatives were synthesised via the dipolar cycloaddition reactions of acrylonitrile, ethyl acrylate and N-arylmaleimides with the nitrile imine regenerated from 2-bromo-1- benzofurylglyoxal-2-[3-phenylpyrazol-5-yl]-hydrazone. Structure of the newly synthesized derivatives were established on the basis of elemental analysis and spectral data


Subject(s)
Pyridazines/chemical synthesis , Acrylonitrile/chemistry , Acrylates/chemistry , Nitriles/chemistry , Imines/chemistry
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